Status:
COMPLETED
Relationships Between the Use of Antimalarial Drugs in Pregnancy and Plasmodium Falciparum Resistance
Lead Sponsor:
London School of Hygiene and Tropical Medicine
Collaborating Sponsors:
DBL -Institute for Health Research and Development
Conditions:
Malaria in Pregnancy
Birth Weight
Eligibility:
FEMALE
15-49 years
Phase:
NA
Brief Summary
Plasmodium falciparum resistance to chloroquine (CQ) and sulfadoxine-pyrimethamine (SP) continue to spread, impeding control of this important disease. CQ and SP are still the most commonly used antim...
Detailed Description
OBJECTIVES Overall objective: To improve the use of malaria chemoprophylaxis in pregnancy. Specific objectives: To investigate the effects of weekly CQ, intermittent presumptive treatment with CQ, a...
Eligibility Criteria
Inclusion
- primi or secundigravidae - seen between 12th and 24th weeks of gestation
- with a non 'at risk pregnancy' (multiple pregnancy, obstetric misproportions, previous caesarean, high blood pressure, diabetes, clinical signs of AIDS.
- staying in a neighbouring district or village
- ability to come for follow-up and delivery.
Exclusion
- • At risk pregnancy
- Severe systemic disease
- Wish to withdraw from participation.
Key Trial Info
Start Date :
October 1 2002
Trial Type :
INTERVENTIONAL
End Date :
March 1 2008
Estimated Enrollment :
700 Patients enrolled
Trial Details
Trial ID
NCT00140517
Start Date
October 1 2002
End Date
March 1 2008
Last Update
January 12 2017
Active Locations (1)
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1
Centre Medicale Paul VI
Ouagadougou, Ouagadougou, Burkina Faso, 01-2099