Status:

COMPLETED

Study to Establish Bioequivalence of ReFacto AF (BDDrFVIII) With Advate (FLrFVIII) in Hemophilia A

Lead Sponsor:

Wyeth is now a wholly owned subsidiary of Pfizer

Conditions:

Hemophilia A

Eligibility:

MALE

12+ years

Phase:

PHASE3

Brief Summary

The study will consist of two parts: a safety and efficacy period in which all subjects will participate and a pharmacokinetic analysis period, in which 30 eligible subjects will participate to compar...

Eligibility Criteria

Inclusion

  • Male subjects with severe or moderately severe hemophilia A
  • A negative past medical history of a Factor VIII inhibitor
  • Age greater than or equal to 12 years

Exclusion

  • A history of Factor VIII inhibitors
  • Presence of a bleeding disorder in addition to hemophilia
  • Known hypersensitivity to hamster protein

Key Trial Info

Start Date :

July 1 2005

Trial Type :

INTERVENTIONAL

End Date :

November 1 2006

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT00141843

Start Date

July 1 2005

End Date

November 1 2006

Last Update

April 22 2008

Active Locations (41)

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Page 1 of 11 (41 locations)

1

Phoenix, Arizona, United States, 85016

2

Sacramento, California, United States, 95817

3

San Diego, California, United States, 92123

4

Aurora, Colorado, United States, 80045