Status:

COMPLETED

NT-proBNP and New Biomarkers in Patients With Dyspnea and/or Peripheral Edema

Lead Sponsor:

Universitätsmedizin Mannheim

Conditions:

Dyspnea

Peripheral Edema

Eligibility:

All Genders

18-90 years

Brief Summary

The objectives of this study are to: * Evaluate the sensitivity and specificity of NT-proBNP (N-terminal prohormone brain natriuretic peptide) and new biomarker measurements for the diagnosis of hear...

Detailed Description

Primary endpoint: * Sensitivity and specificity of biomarker measurements for discrimination of heart failure from dyspnea of other origin. Secondary endpoints: * Determination of Cut-off(s) * Disc...

Eligibility Criteria

Inclusion

  • Age 18-90 years
  • Dyspnea or/and peripheral edema
  • Informed consent

Exclusion

  • Renal insufficiency with creatinine \> 2.8mg/dl
  • Anemia (hemoglobin \< 8.0mg/dl)
  • Pregnancy

Key Trial Info

Start Date :

June 1 2005

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2019

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT00143793

Start Date

June 1 2005

End Date

December 1 2019

Last Update

August 27 2020

Active Locations (1)

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Medical Faculty Mannheim, University of Heidelberg

Mannheim, Baden-Wurttemberg, Germany, 68167