Status:

COMPLETED

Body Composition, Glucose Metabolism, Insulin Resistance and Gene Expression in Muscle Cells in Healthy Overweight Women

Lead Sponsor:

Odense University Hospital

Conditions:

Obesity

Type 2 Diabetes

Eligibility:

FEMALE

18-45 years

Brief Summary

In this study, we will clarify the degree of insulin resistance and characterise muscle glucose metabolism and gene expression in a group of overweight healthy women. The study will clarify how overwe...

Eligibility Criteria

Inclusion

  • Regular menses, i.e. cyclus length 25-34 days
  • Premenopausal
  • Ferrimann-Gallway score \< 2
  • BMI \> 27 kg/m2
  • normal total testosterone value \< 3.5 nmol/l

Exclusion

  • Age \<18 years
  • Contraceptive pills within the past 3 months
  • Postmenopausal (increased FSH)
  • Diabetes mellitus
  • Endocrine or other disease requiring treatment
  • Eating disorder or other psychiatric history
  • Drug use known to influence parameters investigated in this trial
  • Pregnancy

Key Trial Info

Start Date :

September 1 2002

Trial Type :

OBSERVATIONAL

End Date :

December 1 2007

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT00145392

Start Date

September 1 2002

End Date

December 1 2007

Last Update

June 24 2008

Active Locations (1)

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Department of Endocrinology, Odense University Hospital

Odense, Funen, Denmark, 5000