Status:
UNKNOWN
Usefulness of FDG-PET for Advanced Cervical Cancer
Lead Sponsor:
Chang Gung Memorial Hospital
Collaborating Sponsors:
National Science and Technology Council, Taiwan
Conditions:
Cervical Cancer
Eligibility:
FEMALE
Phase:
PHASE3
Brief Summary
The objective of this study is to determinate whether the adding of FDG-PET is helpful in the treatment of advanced cervical cancer with concurrent chemoradiation.
Detailed Description
Concurrent radiotherapy and chemotherapy is the standard treatment for locally advanced cervical cancer. The radiation field should be adjusted according to the extension of disease, especially the pr...
Eligibility Criteria
Inclusion
- Newly diagnosed cervical cancer clinical stage FIGO I -IVA
- Histologically proven cervical carcinoma (including histologic types of squamous cell carcinoma, adenocarcinoma, adenosquamous carcinoma, adenoid cystic carcinoma, lymphoepithelial-like carcinoma and malignant mixed mullerian tumor)
- Presence of at least one enlarged pelvic lymph node (\>=1.0 cm in its maximal dimension), or group of small pelvic nodes (size \<1 cm), and without suspicious para-aortic lymph node metastasis or any lesion outside the pelvis by conventional MRI or CT study
- Karnofsky performance scale \>=60
- Available for concurrent chemoradiation therapy of curative intent
Exclusion
- Cervical tumor with histologic diagnosis of verrucous carcinoma or small cell carcinoma
- Other serious illness or medical condition which would interfere with extended field irradiation or chemotherapy
- Past or current history of malignancy, except for curatively treated non-melanoma skin cancer
- Patients not suitable to receive PET study either by technical or psychological reasons
- Patients who are judged to be noncompliant to treatment or not accessible for follow up
Key Trial Info
Start Date :
January 1 2002
Trial Type :
INTERVENTIONAL
End Date :
December 1 2007
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT00146458
Start Date
January 1 2002
End Date
December 1 2007
Last Update
September 20 2006
Active Locations (1)
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1
Department of Radiation Oncology, Chang Gung Memorial Hospital
Taoyuan District, Taiwan, 333