Status:
UNKNOWN
The Effect of Thyroid Hormone Levels in Pregnant Women on the Intelligence Quotient (IQ) of Their Children
Lead Sponsor:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Conditions:
Child Development Disorders
Pregnancy
Eligibility:
FEMALE
Brief Summary
This study is designed to test the hypothesis that the level of the thyroid hormone thyroxine (specifically, free thyroxine, FT4) circulating in the blood of pregnant women is the key thyroid-related ...
Detailed Description
Summary: The purpose of the proposed study is to test the hypothesis that the key thyroid-related factor in early fetal brain development is T4 derived from the maternal circulation. According to thi...
Eligibility Criteria
Inclusion
- Pregnant female
- Normal TSH in second trimester
- Singleton pregnancy
- Term infant weighing 2500g or more
- No congenital abnormalities noted on birth record
- Delivery in Maine at 36 weeks or later
Exclusion
- TSH levels outside normal range in second trimester
- Pre-existing hypothyroidism, treated
- More than one fetus
- Premature and/or low birth weight infant
- Congenital abnormalities noted on birth record
Key Trial Info
Start Date :
February 1 2004
Trial Type :
OBSERVATIONAL
End Date :
November 1 2008
Estimated Enrollment :
5000 Patients enrolled
Trial Details
Trial ID
NCT00147433
Start Date
February 1 2004
End Date
November 1 2008
Last Update
March 31 2006
Active Locations (1)
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1
Foundation for Blood Research
Scarborough, Maine, United States, 04021