Status:

COMPLETED

Effects of Risperdal Consta on Ability to Benefit From Social Skills Training in Schizophrenia

Lead Sponsor:

University of Illinois at Chicago

Collaborating Sponsors:

Janssen, LP

Weill Medical College of Cornell University

Conditions:

Schizophrenia

Schizoaffective Disorder

Eligibility:

All Genders

18-55 years

Phase:

PHASE3

Brief Summary

The specific aim of this study is to determine whether the new, long-acting, form of risperidone, Risperdal Consta, improves the ability of schizophrenia patients to benefit from skills training. The ...

Detailed Description

The study will be conducted at the University of Illinois at Chicago and New York Presbyterian Hospital-Westchester Division. Patients with schizophrenia or schizoaffective disorder who are considered...

Eligibility Criteria

Inclusion

  • Schizophrenia or schizoaffective disorder
  • Ages 18-55
  • Ability to give informed consent
  • Good general physical health or stable chronic medical conditions
  • Ability to be on a single antipsychotic medication
  • History of inattentiveness in psychosocial treatment settings
  • Poor social skills
  • Must be receiving a single antipsychotic medication
  • Must be clinically stable - defined by the absence of prominent delusions, hallucinations, disorganized speech, or grossly disorganized or catatonic behavior. However, there must also be continuing evidence of impairment, as indicated by the presence of negative symptoms or two or more symptoms of schizophrenia listed in Criterion A of the DSM-IV, in attenuated form (e.g., odd beliefs, unusual perceptual experiences).

Exclusion

  • Inability to give informed consent
  • Substance dependency in the past 6 months
  • Diagnosis of dementia
  • Significant head injury or other brain injury leading to cognitive impairment
  • Mental retardation (premorbid IQ \< 65)
  • Pregnant or nursing
  • Allergy or other significant adverse reaction to risperidone
  • Contraindication to Risperdal Consta as only antipsychotic
  • Currently taking risperidone

Key Trial Info

Start Date :

September 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2006

Estimated Enrollment :

5 Patients enrolled

Trial Details

Trial ID

NCT00148083

Start Date

September 1 2005

End Date

March 1 2006

Last Update

May 15 2019

Active Locations (2)

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Page 1 of 1 (2 locations)

1

University of Illinois at Chicago

Chicago, Illinois, United States, 60612

2

New York Presbyterian Hospital

White Plains, New York, United States, 10605