Status:

COMPLETED

Trial of Asthma Patient Education (TAPE)

Lead Sponsor:

American Lung Association Asthma Clinical Research Centers

Collaborating Sponsors:

National Heart, Lung, and Blood Institute (NHLBI)

Conditions:

Asthma

Eligibility:

All Genders

15+ years

Phase:

PHASE4

Brief Summary

The purpose of this research study is to investigate the way that educational approaches and presentation of a drug may affect the response to montelukast and placebo (an inactive medication) in subje...

Detailed Description

This is a study of the effects of education and drug presentation on efficacy of montelukast and placebo in asthma. This trial will answer the following questions: 1) Is there a true placebo response ...

Eligibility Criteria

Inclusion

  • age 15 or older
  • physician diagnosed asthma
  • regular use of prescribed asthma medication over preceding year
  • post-bronchodilator FEV1 of at least 75% of predicted
  • inadequate asthma control over preceding two months

Exclusion

  • current or past smoking (greater than 10 pack-years)
  • serious asthma exacerbation within previous three months
  • regular use of oral corticosteroids
  • history of respiratory failure due to asthma
  • current use of montelukast or history of adverse reaction to montelukast
  • concomitant interfering medical condition
  • participation in another clinical trial
  • inability or unwillingness to perform study procedures
  • pregnancy, lack of effective contraception (when appropriate), lactation

Key Trial Info

Start Date :

December 1 2003

Trial Type :

INTERVENTIONAL

End Date :

December 1 2005

Estimated Enrollment :

600 Patients enrolled

Trial Details

Trial ID

NCT00148408

Start Date

December 1 2003

End Date

December 1 2005

Last Update

April 30 2010

Active Locations (20)

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Page 1 of 5 (20 locations)

1

University of Alabama at Birmingham

Birmingham, Alabama, United States, 35233

2

University of California at San Diego

San Diego, California, United States, 92103

3

National Jewish Hospital

Denver, Colorado, United States, 80206

4

Nemour's Childrens Center

Jacksonville, Florida, United States, 32207