Status:
COMPLETED
Pre-Emptive Analgesia Efficacy of Etoricoxib for Postoperative Pain
Lead Sponsor:
Khon Kaen University
Conditions:
a Single-Dose of Etoricoxib
Post-Operative Morphine Consumption
Eligibility:
FEMALE
15-65 years
Phase:
PHASE3
Brief Summary
Taken together, studies of the value of pre-emptive analgesia are inconclusive. This randomized, double-blind, dose-ranging, placebo-controlled study was therefore designed to test that a reduction in...
Detailed Description
Patients undergoing transabdominal hysterectomy were randomized to a group taking a single dose (orally) of etoricoxib 120 mg (n = 18), etoricoxib 180 mg (n = 17) or placebo (n = 15) 2 hours before su...
Eligibility Criteria
Inclusion
- The ASA I or II patients undergoing elective transabdominal hysterectomy with general anesthesia
Exclusion
- Patients with history of opioid addiction or chronic pain
- Allergy to other nonsteroidal anti-inflammatory, or asthma
- Concomitant use of tricyclic antidepressants, opioid analgesics, antihistamines, tranquilizers, hypnotics, sedatives, or systemic corticosteroids
- Those unable to understand the principle of patient-controlled analgesia(PCA) device were excluded from the study
Key Trial Info
Start Date :
December 1 2004
Trial Type :
INTERVENTIONAL
End Date :
May 1 2005
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00149253
Start Date
December 1 2004
End Date
May 1 2005
Last Update
September 8 2005
Active Locations (1)
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1
Warporn Chau-in
KhonKaen University, KhonKaen, Thailand, 40002