Status:
COMPLETED
Omega-3-Polyunsaturated Fatty-Acids (N3-Pufa) In Patients With Severe Chronic Heart Failure
Lead Sponsor:
Medical University of Vienna
Conditions:
Chronic Heart Failure
Eligibility:
All Genders
18+ years
Phase:
PHASE2
PHASE3
Brief Summary
To investigate whether n3-fatty acids have beneficial effects in chronic heart failure as regards circulatory function.
Eligibility Criteria
Inclusion
- Chronic heart failure of non-ischemic origin
- Age ≥18 years
- NYHA functional class III-IV
- LVEF \< 35 %
- Optimized heart failure therapy
- plasma NT-BNP \>2000pg/ml
Exclusion
- Current treatment with Omacor or other fish oil products
- Known hypersensitivity to the study drug
- Ischemic cardiomyopathy
- Uncorrected significant valvular heart disease
- Heart failure due to congenital heart disease
- Restrictive cardiomyopathy
- Alcoholic heart disease
- Acute myocarditis
- Continuous i.v. therapy for heart failure
- Mechanical assist device
- Life expectancy \<1 year due to non-cardiac causes
- Inability to perform bicycle testing
- Women of childbearing potential not practicing a save contraception method
- Current participation in another intervention study
- Participation in another study with an intervention within the last 3 months.
Key Trial Info
Start Date :
September 1 2005
Trial Type :
INTERVENTIONAL
End Date :
February 1 2008
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00149409
Start Date
September 1 2005
End Date
February 1 2008
Last Update
July 13 2010
Active Locations (1)
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1
Medical University of Vienna
Vienna, Austria, A-1090