Status:

COMPLETED

Effectiveness of Escitalopram in the Treatment of Body Dysmorphic Disorder

Lead Sponsor:

Massachusetts General Hospital

Collaborating Sponsors:

National Institute of Mental Health (NIMH)

Rhode Island Hospital

Conditions:

Anxiety Disorders

Somatoform Disorders

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

This study's primary aim is to compare time to relapse and relapse rates in responders to acute escitalopram who are then randomized to placebo versus continuation treatment with escitalopram.

Detailed Description

We propose to conduct the first pharmacotherapy relapse prevention study in body dysmorphic disorder (BDD). BDD, an often-delusional preoccupation with a nonexistent or slight defect in appearance, is...

Eligibility Criteria

Inclusion

  • Outpatient men and women age 18 and older
  • Diagnosis of BDD within 6 months of study start date based on the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV)
  • Score of 24 or higher on the BDD-Yale-Brown Obsessive Compulsive Scale
  • Lives within driving distance of Boston, MA or Providence, RI

Exclusion

  • Suicidal or homicidal tendencies
  • Alcohol/drug abuse or dependence within 3 months of study entry

Key Trial Info

Start Date :

May 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2013

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT00149799

Start Date

May 1 2005

End Date

March 1 2013

Last Update

December 5 2017

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Massachusetts General Hospital

Boston, Massachusetts, United States, 02114

2

Rhode Island Hospital

Providence, Rhode Island, United States, 02906