Status:

COMPLETED

Antithyroid Drugs During Radioiodine Therapy

Lead Sponsor:

Odense University Hospital

Conditions:

Toxic Nodular Goitre

Graves Disease

Eligibility:

All Genders

18-85 years

Phase:

PHASE4

Brief Summary

Background: The use of radioactive iodine (131I) therapy as the definite cure of hyperthyroidism is widespread. According to a survey on the management of Graves' disease, thirty per cent of physician...

Eligibility Criteria

Inclusion

  • Hyperthyroid patients going to be treated with radioiodine either due to recurrent Graves' disease or toxic nodular goiter.

Exclusion

  • Age \< 18 yrs.
  • Allergy to anti-thyroid drugs
  • Substernal or large (\> 100ml) goiter
  • Severe endocrine ophthalmopathy
  • Pregnancy or lactation
  • Suspicion of thyroid malignancy
  • Unsafe contraconception
  • Physical or mental condition that hinders corporation

Key Trial Info

Start Date :

January 1 2003

Trial Type :

INTERVENTIONAL

End Date :

December 1 2004

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT00150137

Start Date

January 1 2003

End Date

December 1 2004

Last Update

February 3 2006

Active Locations (1)

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1

Department of Endocrinology, Odense University Hospital

Odense, Funen, Denmark, 5000