Status:
UNKNOWN
Home UVB Phototherapy for Psoriasis: Effectiveness, Quality of Life and Cost-Effectiveness
Lead Sponsor:
UMC Utrecht
Collaborating Sponsors:
ZonMw: The Netherlands Organisation for Health Research and Development
Conditions:
Psoriasis
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
UVB phototherapy is a commonly used treatment for patients with psoriasis. Generally it is performed in the outpatient department of the hospital. The UVB irradiation itself will normally take only a ...
Detailed Description
Psoriasis is a chronic recurrent skin disorder characterised by erythematosquamous lesions (plaques). Usually the abnormal areas are few, but occasionally the disease is more generalised. Psoriasis ca...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Guttate or plaque psoriasis, clinically eligible for narrowband UVB (TL-01) phototherapy;
- Willing to undergo treatment according to randomisation.
- Exclusion criteria:
- No informed consent:
- age below 18 years;
- not willing to accept one of the two treatments offered;
- Practical reasons:
- not able to receive one of the two treatments offered (e.g. lack of space at home / living too far from hospital etc.);
- analphabetism (unable to read the patient-information and the questionnaires, unable to provide written answers and written informed consent);
- lack of knowledge of the Dutch language;
- not in possession of a telephone.
- Expected non-compliance: lack of understanding what the study / treatment is about, with its potential consequences.
- Medical contra-indications:
- malignancy of the skin in the past / at present;
- known UVB-allergy or chronic polymorphic photodermatosis;
- use (at time of inclusion) of (systemic) medication with known phototoxic or photoallergic properties;
- use (at time of inclusion) of systemic antipsoriatic medication (cyclosporin, methotrexate, neotigason, fumaric acid);
- history of exposure to ionising radiation.
Exclusion
Key Trial Info
Start Date :
October 1 2002
Trial Type :
INTERVENTIONAL
End Date :
March 1 2005
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT00150930
Start Date
October 1 2002
End Date
March 1 2005
Last Update
November 28 2006
Active Locations (1)
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1
UMC Utrecht
Utrecht, Netherlands, 3584 CX