Status:
TERMINATED
Orthotopic Liver Transplantation Using a Living Donor
Lead Sponsor:
University of Chicago
Conditions:
Liver Disease
Liver Neoplasms
Eligibility:
All Genders
18-55 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to: determine the safety of donor right hepatic lobectomy as a procedure to provide a liver graft for living donor liver transplantation. study the regeneration of liver...
Detailed Description
Preoperative Evaluation of Recipients: Recipients who consent for living donor liver transplantation will have the following measurements performed in addition to those normally performed in their pr...
Eligibility Criteria
Inclusion
- Age 18-55
- No current or prior history of heart, lung or other medical problems.
- No history of liver disease.
- No history of malignancy, except limited basal cell carcinoma.
- ABO / HLA compatibility with the recipient.
- If female and premenopausal, a negative pregnancy test.
- Related to recipient either by blood or marriage and having a stable, long term, emotional relationship.
- The donor's body size and volumetric determination of liver mass by abdominal CT scan will indicate whether or not a donor is a suitable candidate for liver donation if the donor meets the other inclusion criteria. Favorable donors for the individual organs will be those with donor graft to recipient body dry weight ratios (GRBWR) of \>0.7% and those with a ratio of graft volume to recipient's expected liver volume (GWRLW) of \>35%.
- Satisfactory psychosocial evaluation. -
Exclusion
- Recipient
Key Trial Info
Start Date :
April 1 2000
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2006
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00152607
Start Date
April 1 2000
End Date
September 1 2006
Last Update
September 27 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
The University of Chicago Hospitals
Chicago, Illinois, United States, 60637