Status:

COMPLETED

Study to Eliminate Hib Carriage in Rural Alaska Native Villages

Lead Sponsor:

Centers for Disease Control and Prevention

Collaborating Sponsors:

CDC-Arctic Investigations Program

Alaska Native Tribal Health Consortium

Conditions:

Haemophilus Influenzae Type B

Carrier State

Eligibility:

All Genders

Phase:

PHASE4

Brief Summary

Hib disease rates in rural Alaska before introduction of HIb conjugate vaccine were among the highest in the world. Since vaccine introduction, rates have fallen by 90% but the disease has not been el...

Detailed Description

This was a pilot intervention to assess the feasibility of using Hib conjugate vaccine to eliminate Hib carriage in rural Alaska villages, with three villages to serve as a comparison group. WE perfor...

Eligibility Criteria

Inclusion

  • All village residents are eligible for Hib colonization survey
  • All residents of selected villages eligible for vaccine study except as noted below.

Exclusion

  • For receipt of vaccine:
  • history of allergic reaction to Hib vaccine or components
  • Age \< 24 months and not due for Hib vaccine according to childhood immunization schedule
  • Age \> 24 months and have received HIb vaccine within past year
  • Pregnant

Key Trial Info

Start Date :

September 1 2001

Trial Type :

INTERVENTIONAL

End Date :

November 1 2003

Estimated Enrollment :

3200 Patients enrolled

Trial Details

Trial ID

NCT00153556

Start Date

September 1 2001

End Date

November 1 2003

Last Update

September 12 2005

Active Locations (1)

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Page 1 of 1 (1 locations)

1

CDC Arctic Investigations Program

Anchorage, Alaska, United States, 99508