Status:
COMPLETED
Intravenous Pantoloc In Aspirin-Induced Ulcer Bleeding
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Cardiovascular Disease
Cerebrovascular Disorders
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
The aim of the study is to investigate whether intravenous infusion of pantoprazole (Pantoloc) is effective in preventing recurrent bleeding in patients who present with acute ulcer bleeding and conti...
Detailed Description
Aspirin is an effective treatment for acute stroke and heart attack. However, aspirin also induces ulcer and provokes acute ulcer bleeding. Thus, aspirin is often withheld in acute ulcer bleeding but ...
Eligibility Criteria
Inclusion
- Patients received daily anti-platelet therapy for vascular prophylaxis before admission and will continue need to do so
- Patinets with bleeding peptic ulcers;ulcer actively bleeding or with SRH (Forrest I, IIa and IIb ulcers)
- Endoscopic haemostasis achieved
Exclusion
- Presence of ulcer complication precluding endoscopic treatment such as gastric outlet obstruction or ulcer perforation mandating surgical intervention.
- Concomitant use of anticoagulant, NSAIDs or steroid
- Pending to undergo cardiac interventions that need double anti-platelet agent
- Pregnancy
- Terminal illness, or cancer
Key Trial Info
Start Date :
February 1 2003
Trial Type :
INTERVENTIONAL
End Date :
September 1 2006
Estimated Enrollment :
156 Patients enrolled
Trial Details
Trial ID
NCT00153725
Start Date
February 1 2003
End Date
September 1 2006
Last Update
October 27 2006
Active Locations (3)
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1
Endoscopy Center, North District Hospital
Hong Kong, China
2
Endoscopy Center, Prince of Wales Hospital
Hong Kong, China
3
Endoscopy Center, United Christian Hospital
Hong Kong, China