Status:
COMPLETED
Investigation of Vascular Relaxing Effects of Candesartan and Pioglitazone.
Lead Sponsor:
Technische Universität Dresden
Conditions:
Healthy Subjects
Eligibility:
MALE
18-40 years
Phase:
NA
Brief Summary
The study is designed to test the hypothesis in healthy subjects that candesartan and pioglitazone provide additional vascular relaxing or modulating effects in addition to their blood-pressure and bl...
Detailed Description
The aim of the study is to investigate the effect of oral candesartan and/ or rosiglitazone therapy on the vascular responsiveness of different vasoactive compounds (angiotensin II, insulin, histamine...
Eligibility Criteria
Inclusion
- Male
- healthy
- 18 - 40 years old
- non-smoker
- no additional medication
Exclusion
- any relevant disease
- smokers
- elevated liver enzymes
- body weight different from Broca Norm \> 20%
- allergies
Key Trial Info
Start Date :
October 1 2005
Trial Type :
INTERVENTIONAL
End Date :
September 1 2006
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00154037
Start Date
October 1 2005
End Date
September 1 2006
Last Update
September 13 2006
Active Locations (1)
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1
Institute of Clinical Pharmacology, Medical Faculty, University of Technology
Dresden, Germany, 01307