Status:
UNKNOWN
24 Hour Esophageal and Electrogastrography to Investigate the Mechanism of Reflux Esophagitis
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Reflux Esophagitis
Eligibility:
All Genders
18-85 years
Brief Summary
We hypothesize that gastric dysrhythmias may predispose the occurrence of gastroesophageal reflux.
Detailed Description
Gastroesophageal regurgitation with acid is considered the main cause of reflux esophagitis, but the current theory of transient relaxation of LES (TLESR) fails to explain all the mechanisms of reflux...
Eligibility Criteria
Inclusion
- GERD questionnaire with heartburn or acid regurgitation with a frequency at least once weekly.
- Endoscopic esophagitis.
Exclusion
- A history of esophageal, gastric or abdominal surgery.
- Gastric or esophageal cancer.
- Esophageal varices.
- Concomittant severe systemic disease.
Key Trial Info
Start Date :
February 1 2004
Trial Type :
OBSERVATIONAL
End Date :
August 1 2005
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00154570
Start Date
February 1 2004
End Date
August 1 2005
Last Update
November 22 2005
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taiwan, 10016