Status:
COMPLETED
Kallikrein-kinin (KKS) and Renin-angiotensin-aldosterone System (RAAS) in Primary Aldosteronism
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Hyperaldosteronism
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
The tissue kallikrein-kinin (KKS) and renin-angiotension-aldosterone system (RAAS) had been implicated in regulating blood pressure and electrolyte homeostasis. Both of the KKS and RAAS may work coord...
Detailed Description
Hypertension affects 20% to 25% of adult population. Most patients are diagnosed as having essential or primary hypertension. Up to 10% to 15 % have an identifiable cause and many of those have an adr...
Eligibility Criteria
Inclusion
- Patients with hypertension admitted for the diagnosis of primary aldosteronism
Exclusion
- Pregnant or lactating women. (Pre-menopause women, capable of bearing children will undergo pregnancy test), hypertension without discontinuous b-blocker, ACEI or ARB for more than 10 days.
Key Trial Info
Start Date :
July 1 2002
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2005
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00155064
Start Date
July 1 2002
End Date
December 1 2005
Last Update
December 17 2014
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taiwan