Status:

UNKNOWN

Effect of Polymorphisms in the IL-1 Gene Complex on the Development of Chronic Hepatitis and Hepatocellular Carcinoma

Lead Sponsor:

National Taiwan University Hospital

Collaborating Sponsors:

National Science and Technology Council, Taiwan

Conditions:

Hepatitis B

Carcinoma, Hepatocellular

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to determine the effect of polymorphisms in the IL-1 gene complex on the development of chronic hepatitis and hepatocellular carcinoma.

Detailed Description

We analyzed single-nucleotide polymorphisms in the genes for interleukin-1a, interleukin-1b, interleukin-1-receptor antagonist, interleukin-1-receptor type I, and interleukin-1-receptor type II in 400...

Eligibility Criteria

Inclusion

  • Normal controls
  • Cases of chronic hepatitis and hepatocellular carcinoma

Exclusion

  • Pregnant women

Key Trial Info

Start Date :

August 1 2004

Trial Type :

OBSERVATIONAL

End Date :

Estimated Enrollment :

1600 Patients enrolled

Trial Details

Trial ID

NCT00155103

Start Date

August 1 2004

Last Update

March 21 2007

Active Locations (1)

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1

Department of Medical Genetics; National Taiwan University Hospital

Taipei, Taipei, Taiwan, 100