Status:
UNKNOWN
Mesothelin as a New Tumor Marker for Ovarian Cancer
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Ovarian Cancer
Eligibility:
FEMALE
15-90 years
Brief Summary
Ovarian cancer became a more and more important disease in recent years due to its first mortality rate of gynecologic malignancies. The incidence of ovarian cancer also increased in recent year in Ta...
Detailed Description
Incidence of Ovarian Cancer Ovarian cancer is the first mortality rate of gynecologic malignancies (1-3) and became a more and more important disease in recent years (4-6). The incidence of ovarian ca...
Eligibility Criteria
Inclusion
- \- Patients with ovarian carcinoma who undergo hysterectomy, bilateral salpingo-oophorectomy, omentectomy, and appendectomy will be enrolled and the clinical data will be obtained from our hospital. All of the patients received four to six courses of adjuvant platinum-containing chemotherapy.Histologic grading was according to International Union against Cancer criteria (28). The stage of disease was classified according to the International Federation of Gynecology and Obstetrics (FIGO, 1987). Pelvic and paraaortic lymph node samplings will be performed, if the disease will be confined to within the ovary or will be without a ruptured capsule. The histopathologic data, including histologic type and histologic grade, will be evaluated by a certified pathologist. The maximal diameter of the residual tumor after surgery will be also recorded. All patients will be followed up at 3-month intervals.
- Patients with ovarian endometrioma, other benign ovarian tumors receiving surgical intervention, or healthy patients without surgical intervention will be presented as normal controls.
Exclusion
- \-
Key Trial Info
Start Date :
January 1 2002
Trial Type :
OBSERVATIONAL
End Date :
December 1 2006
Estimated Enrollment :
250 Patients enrolled
Trial Details
Trial ID
NCT00155740
Start Date
January 1 2002
End Date
December 1 2006
Last Update
November 28 2005
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taiwan