Status:
COMPLETED
MDA D-Dimer / Recurrent DVT Study
Lead Sponsor:
McMaster University
Collaborating Sponsors:
Canadian Institutes of Health Research (CIHR)
Conditions:
Deep Vein Thrombosis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
To determine whether treatment and further investigation can be safely withheld in patients who present with suspected recurrent deep vein thrombosis (DVT) and have either a (i) negative D-Dimer or (i...
Eligibility Criteria
Inclusion
- Age 18 or older
- Currently suspected for recurrent DVT
- Has a prior history of objectively documented DVT or PE
Exclusion
- Comorbid condition limiting survival to less than 3 months
- History of hypersensitivity to contrast medium
- Renal dysfunction with a creatinine of \> 150 mcmol/L
- Treatment with full-dose therapeutic unfractionated or low molecular weight heparin that was initiated 24 hours or more prior to eligibility assessment
- Pregnancy or lactation
- Symptomatic for pulmonary embolism
- Absence of symptoms within five days prior to presentation
- Participation in another trial precluding the use of the diagnostic algorithm in this study
- Geographically inaccessible for follow-up
- Compression ultrasound, venogram, IPG, or D-dimer performed PRIOR to assessment
Key Trial Info
Start Date :
January 1 2002
Trial Type :
INTERVENTIONAL
End Date :
March 1 2007
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT00157599
Start Date
January 1 2002
End Date
March 1 2007
Last Update
July 26 2011
Active Locations (6)
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1
Hamilton General Hospital
Hamilton, Ontario, Canada, L8L 2X2
2
McMaster University Medical Centre
Hamilton, Ontario, Canada, L8N 3Z5
3
St. Joseph's Hospital
Hamilton, Ontario, Canada, L8N 4A6
4
Henderson Research Centre
Hamilton, Ontario, Canada, L8V 1C3