Status:
COMPLETED
Selective D-Dimer Testing Compared With Uniform D-Dimer Testing in the Diagnosis of Deep Vein Thrombosis (SELECT)
Lead Sponsor:
McMaster University
Collaborating Sponsors:
Heart and Stroke Foundation of Ontario
Conditions:
Deep Vein Thrombosis
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The purpose of this study is to compare two diagnostic interventions to improve the way D-dimer blood testing (MDA D-dimer) is used to diagnose first time symptomatic deep vein thrombosis.
Detailed Description
* Limiting use of D-dimer testing to outpatients with a Low or Moderate clinical pretest probability (C-PTP)for deep vein thrombosis AND using a D-dimer level of \< 1.0 µg FEU/mL to exclude deep vein ...
Eligibility Criteria
Inclusion
- Age 18 and older
- Presenting with symptoms compatible with clinically suspected deep vein thrombosis
Exclusion
- Treatment with full dose anticoagulation for 24 hours or more.
- Other test for deep vein thrombosis already performed.
- Ongoing need for therapeutic anticoagulant therapy.
- Life expectancy less than 3 months.
- Absence of acute symptoms within 7 days of presentation.
- Presenting with symptoms of pulmonary embolism.
- Previous confirmed episode of deep vein thrombosis or pulmonary embolism.
- Current pregnancy.
- Geographic inaccessibility which precludes follow-up.
Key Trial Info
Start Date :
October 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2010
Estimated Enrollment :
1727 Patients enrolled
Trial Details
Trial ID
NCT00157677
Start Date
October 1 2004
End Date
June 1 2010
Last Update
October 27 2011
Active Locations (5)
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1
Hamilton Health Sciences, McMaster
Hamilton, Ontario, Canada, L8N 3Z5
2
St. Joseph's Health Care Centre
Hamilton, Ontario, Canada, L8N 4A6
3
Hamilton Health Sciences, Henderson
Hamilton, Ontario, Canada, L8V 1C3
4
Hamilton Health Sciences, General
Hamilton, Ontario, Canada