Status:
COMPLETED
Effects of Citicoline on Brain Function and Behavior in Marijuana-Dependent Individuals
Lead Sponsor:
Mclean Hospital
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Marijuana Abuse
Eligibility:
All Genders
18-45 years
Phase:
PHASE2
Brief Summary
The Three Aims of this study are (only studies for Aim 1 were completed) 1. Measure the impact of citicoline on marihuana use patterns in subjects' individualized natural settings and responses to ma...
Detailed Description
Marijuana dependence is an important public health problem in the United States, yet still no effective therapies are available. It is unclear how marijuana affects brain function after acute or chron...
Eligibility Criteria
Inclusion
- Meets DSM-IV criteria for current marijuana dependence
- Women with a negative pregnancy test prior to study entry
- Heavy smoker, defined as smoking more than 10 joints per week
Exclusion
- Abnormal electrocardiogram (ECG)
- Medical disorder that requires prescription medication
- Psychiatric disorder that requires prescription medication
- Abnormal liver function tests
- Taking herbal preparations
- Taking any over-the-counter medications on a chronic basis
- Pregnancy or breast feeding
- Neurological, infectious, or neoplastic disease
- Currently seeking treatment for marijuana abuse
- Meets criteria for alcohol, cocaine, or opioid dependence
Key Trial Info
Start Date :
September 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2014
Estimated Enrollment :
21 Patients enrolled
Trial Details
Trial ID
NCT00158249
Start Date
September 1 2009
End Date
October 1 2014
Last Update
October 22 2014
Active Locations (1)
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1
McLean Hospital, Department of Psychiatry
Belmont, Massachusetts, United States, 02478 9106