Status:
COMPLETED
HLA Sensitization Following Major Cortical Allograft Bone Procedures
Lead Sponsor:
University of Florida
Conditions:
Bone Cancer
Eligibility:
All Genders
12-80 years
Brief Summary
The purpose of this study is to find out whether or not antibodies to the donor bone are present in the blood of patients who receive the donor bone.
Detailed Description
Patients who have bone cancer often have the cancerous bone removed by surgery and replaced with a piece of bone taken from a donor (a person who donates parts of their body to be used for transplants...
Eligibility Criteria
Inclusion
- Patients twelve years or older who are scheduled for massive fresh-frozen human structural bone allograft implantation at participating centers will be given the opportunity to participate in the study. All patients must have a reconstruction of the involved long bone with either an intercalary graft, an osteoarticular graft, or an allograft/endoprosthesis composite graft. The junction or union site studied will be the cortical-cortical, host allograft junction site, not the cancellous interfaces.
Exclusion
- Patients who do not require major weight bearing cortical allograft bone grafts will be excluded. Also, women who are or could potentially become pregnant will be excluded from the study.
Key Trial Info
Start Date :
September 1 1999
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2010
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00160719
Start Date
September 1 1999
End Date
March 1 2010
Last Update
October 30 2012
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
UF Orthopaedics and Sports Medicine Institute
Gainesville, Florida, United States, 32611