Status:

COMPLETED

Efficacy of Ciclesonide on Small Airways in Patients With Stable Asthma (18 to 60 y) (BY9010/M1-131)

Lead Sponsor:

AstraZeneca

Conditions:

Asthma

Eligibility:

All Genders

18-60 years

Phase:

PHASE3

Brief Summary

The aim of this study is to evaluate the involvement of small airways in asthma, as determined by bronchial challenges, CT-scanning, and cellular markers of inflammation. Ciclesonide will be inhaled a...

Eligibility Criteria

Inclusion

  • Main
  • Written informed consent
  • History of bronchial asthma
  • FEV1 more than or equal to 60% of predicted
  • Stable asthma
  • Patients who are in good health with the exception of asthma
  • Main

Exclusion

  • Concomitant severe diseases, diseases expected to interfere with the outcome of the study, or diseases which are contraindications for the use of ICS
  • COPD (i.e. chronic bronchitis or emphysema) and/or other relevant lung diseases causing alternating impairment in lung function
  • Use of ICS 4 weeks before entry into the baseline period
  • Pregnancy
  • Intention to become pregnant during the course of the study
  • Breast feeding
  • Lack of safe contraception
  • Use of other drugs not allowed
  • Current smokers and ex-smokers with more than or equal to 10 pack-years

Key Trial Info

Start Date :

September 1 2003

Trial Type :

INTERVENTIONAL

End Date :

May 1 2006

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT00163345

Start Date

September 1 2003

End Date

May 1 2006

Last Update

December 8 2016

Active Locations (1)

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Altana Pharma/Nycomed

RB Groningen, Netherlands, 9700