Status:
TERMINATED
Effect of GABAB Agonist on Visceral Hyperalgesia in NCCP patientsChinese?
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Non-Cardiac Chest Pain
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The effect of baclofen (GABAB agonist), diltiazem (muscle relaxant) and placebo will be compared in a double-blinded randomized study for the treatment of NCCP. Cerebral cortical, brainstem and spinal...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Consecutive patients with monthly angina-like chest pain and negative coronary angiogram or scintigraphy
- Age between 18-70
- Gastroesophageal reflux disease
- Psychiatric illness
- Cerebrovascular accident
- Active peptic ulceration
- Heart failure or cardiac bradyarrhythmia
- Epilepsy
- Pregnancy or lactating female
- Previous hypersensitivity to muscle relaxant
Exclusion
Key Trial Info
Start Date :
November 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2007
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00164801
Start Date
November 1 2004
End Date
January 1 2007
Last Update
March 26 2008
Active Locations (1)
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1
Endoscopy Centre, Prince of Wales Hospital
Hong Kong, China