Status:
COMPLETED
Administration of High-Dose Intravenous Proton Pump Inhibitor for Upper Gastrointestinal Bleeding Prior to Endoscopy
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Peptic Ulcer
Eligibility:
All Genders
16+ years
Phase:
PHASE4
Brief Summary
To evaluate if intravenous PPI infusion, when administered prior to endoscopy, hastens resolution of bleeding stigmata and thereby facilitates endoscopic examinations and reduces the need for endoscop...
Detailed Description
A placebo-controlled randomised study is being proposed. We hypothesize that early administration of intravenous omeprazole infusion stabilizes clots overlying arteries and hastens resolution of bleed...
Eligibility Criteria
Inclusion
- Patients with overt signs of upper GIB; fresh hematemesis and/or melena with or with circulatory compromise
Exclusion
- Chronic aspirin user,
- Pregnancy,
- Age\<16,
- Allergy to PPI,
- No consent
Key Trial Info
Start Date :
February 1 2004
Trial Type :
INTERVENTIONAL
End Date :
September 1 2005
Estimated Enrollment :
638 Patients enrolled
Trial Details
Trial ID
NCT00164866
Start Date
February 1 2004
End Date
September 1 2005
Last Update
June 6 2007
Active Locations (1)
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1
Endoscopy Center, Prince of Wales Hospital
Hong Kong SAR, China