Status:
COMPLETED
Tangential Radiation Therapy Without Axillary Dissection in Breast Cancer
Lead Sponsor:
Dana-Farber Cancer Institute
Collaborating Sponsors:
Brigham and Women's Hospital
Massachusetts General Hospital
Conditions:
Early-Stage Breast Cancer
Eligibility:
All Genders
55+ years
Phase:
PHASE2
Brief Summary
The purpose of this study is to evaluate whether treatment to the axilla (area under the arm) can be safely minimized by omitting axillary surgery and full axillary radiation therapy and replacing it ...
Detailed Description
* Patients will have undergone conservative breast surgery without axillary dissection prior to enrollment in this study. * Patients will receive radiation therapy to the breast, including the lowest ...
Eligibility Criteria
Inclusion
- Patients must have clinical stage I or II breast cancer, clinically uninvolved axillary nodes.
- Patients must be 55 years or older.
- Patients must undergo total excision of the primary invasive tumor
- Final pathologic margin status must be negative
- Only estrogen receptor (ER) or progesterone receptor (PR) positive tumors will be permitted
Exclusion
- Prior history of malignancy, except for non-melanoma skin cancers and carcinoma in situ fo the cervix
Key Trial Info
Start Date :
September 1 1998
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2016
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00165243
Start Date
September 1 1998
End Date
December 1 2016
Last Update
June 7 2017
Active Locations (2)
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1
Dana-Farber Cancer Institute
Boston, Massachusetts, United States, 02115
2
Massachusetts General Hospital
Boston, Massachusetts, United States, 02115