Status:
COMPLETED
Heparin Responses in Pediatric Patients Undergoing Cardiopulmonary Bypass.
Lead Sponsor:
Emory University
Conditions:
Children With Heart Defects
Eligibility:
All Genders
Up to 10 years
Brief Summary
Heparin is an anticoagulant or "blood thinner". Heparin is always given to patients undergoing open-heart surgery to prevent blood from clotting when a patient is placed on the heart-lung machine. Hep...
Detailed Description
Introduction Anticoagulation during cardiopulmonary bypass (CPB) is necessary to prevent clotting as blood comes in contact with the unphysiologic surfaces of the extracorporeal circuit, and is achie...
Eligibility Criteria
Inclusion
- Patients undergoing elective cardiac surgery requiring the use of cardiopulmonary bypass scheduled at Children's Healthcare of Atlanta, Egleston (either a first procedure or a reoperation)
- Patients within the appropriate age groups (birth to 2 years of age, and 10 years or older)
- Parents or legal guardian willing for child to participate and able to sign the provided informed consent -
Exclusion
- Patients undergoing cardiac surgery not requiring the use of CPB
- Patients undergoing any emergent procedure/surgery
- Patients who take preoperative anticoagulant therapy
- Patients with a CPB time greater that 4 hours
- Patients requiring a return to CPB for any reason
- Patients whose parents or legal guardian are unwilling or unable to sign the provided informed consent
- Patients who, in the opinion of the investigators, should not be included in the study
- Patients who are older than 2 years, but less than 10 years of age are excluded
Key Trial Info
Start Date :
December 1 2002
Trial Type :
OBSERVATIONAL
End Date :
May 1 2006
Estimated Enrollment :
125 Patients enrolled
Trial Details
Trial ID
NCT00166140
Start Date
December 1 2002
End Date
May 1 2006
Last Update
November 20 2013
Active Locations (1)
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1
Children's Healthcare of Atlanta at Egleston
Atlanta, Georgia, United States, 30322