Status:
COMPLETED
Cardiopulmonary Bypass and Inflammatory Response
Lead Sponsor:
University of Pittsburgh
Conditions:
Thoracic Surgery
Cardiopulmonary Bypass
Eligibility:
All Genders
18-90 years
Brief Summary
The purpose of this study is to determine if a difference exists in the inflammatory response which occurs related to coronary artery bypass graft (CABG)surgery performed on cardiopulmonary bypass as ...
Detailed Description
Acute inflammatory response occurring in cardiopulmonary bypass (CPB) patients has been clearly associated with deleterious clinical outcomes. Increasing understanding of the pathophysiology of system...
Eligibility Criteria
Inclusion
- Patients undergoing CABG and/or patients undergoing other procedures (i.e., valve surgery, myomectomy, etc.) in addition to coronary revascularization
- Age: 18 years up to and including 90 years
Exclusion
- Patient is not scheduled to undergo CABG surgery
- Ejection Fraction £ 30%
- Chronic renal failure requiring hemodialysis
- Long-term steroid use prior to surgery
- HIV positive patients (HIV testing will not be required to rule out HIV)
- Status post organ transplantation or on immune modulating drugs
- Presence of severe sepsis in the past month prior to surgery
- Prisoners
Key Trial Info
Start Date :
December 1 2003
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2005
Estimated Enrollment :
37 Patients enrolled
Trial Details
Trial ID
NCT00167349
Start Date
December 1 2003
End Date
January 1 2005
Last Update
April 15 2011
Active Locations (1)
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1
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15261