Status:
COMPLETED
Soybean Based Diets and CVD Risk Factors
Lead Sponsor:
Tufts University
Conditions:
Hypercholesterolemia
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
To evaluate the impact of soybean processing as well as the effect of soy relative to animal protein, independent of alterations in the fatty acid profile of the diet on CVD risk factors in hyperchole...
Detailed Description
Recent data suggests that the magnitude of the effect of soy protein on lipid and lipoprotein levels is variable and less dramatic than originally reported. This discordance might be attributable to t...
Eligibility Criteria
Inclusion
- Plasma LDL-C \>120mg/dL, Free from chronic illness, Not taking medications known to affect lipid metabolism (lipid lowering drugs, beta-blockers, fish-oil capsules, cis-retinoic acid, ascorbic acid, vitamin E, diuretics or hormones), Post-menopausal women.
Exclusion
- Soy allergy, Smokers, Consuming \>2 alcoholic drinks per day, Pre-menopausal women.
Key Trial Info
Start Date :
June 1 2001
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2005
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00175097
Start Date
June 1 2001
End Date
May 1 2005
Last Update
December 2 2014
Active Locations (2)
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1
Division of Cardiology, Tufts-New England Medical Center Hospitals, Tufts University School of Medicine
Boston, Massachusetts, United States, 02111
2
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University
Boston, Massachusetts, United States, 02111