Status:
COMPLETED
Prevention of Contrast-Induced Nephropathy
Lead Sponsor:
University of Alberta
Collaborating Sponsors:
Alberta Heritage Foundation for Medical Research
Conditions:
Contrast-induced Nephropathy
Acute Renal Failure
Eligibility:
All Genders
21+ years
Phase:
NA
Brief Summary
Patients with pre-existing kidney disease are at high risk of acute renal failure when exposed to radio-contrast dyes, for example during a cardiac angiogram. The investigators hypothesize that an in...
Detailed Description
Patients with pre-existing kidney disease are at high risk of acute renal failure when exposed to radio-contrast dyes, for example during a cardiac angiogram. We hypothesize that an infusion of salin...
Eligibility Criteria
Inclusion
- age \> 21 years
- serum creatinine \> 150 umol/L
- able and willing to provide informed consent
Exclusion
- known hypersensitivity to contrast, furosemide, or mannitol
- unable to tolerate a fluid load (e.g., acute pulmonary edema)
- ESRD, on dialysis
- previous enrollment in this study or previous contrast administration with the last 2 weeks
- refusal by treating physician
Key Trial Info
Start Date :
May 1 1996
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT00175227
Start Date
May 1 1996
Last Update
May 10 2011
Active Locations (1)
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1
University of Alberta Hospitals
Edmonton, Alberta, Canada, T6G 2B7