Status:

COMPLETED

Response of Topical Capsaicin in Alopecia Areata

Lead Sponsor:

University of Minnesota

Conditions:

Alopecia Areata

Eligibility:

All Genders

18-70 years

Phase:

PHASE4

Brief Summary

It has been postulated that Alopecia Areata (AA) is, at least in part, a neurologically mediated disease. Research supporting this theory includes the finding that nerves surrounding the hair follicle...

Detailed Description

To assess the function of perifollicular scalp nerves in AA we will look at the response of these nerves to the topical medication capsaicin. Under normal circumstances topical capsaicin is known to t...

Eligibility Criteria

Inclusion

  • Must have alopecia totalis or universalis.
  • Be in good health.
  • Not be taking any medications including topical medications
  • Be 18 years or older.
  • Be willing to apply study medication or vehicle as directed, comply with instructions and commit to follow-up visits.
  • Not have had hair chemically treated (including colored hair, permed hair, etc) within the month prior to the study.

Exclusion

  • Absence of extensive alopecia areata.
  • People not in good health.
  • People taking medications.
  • Allergies to capsaicin.
  • Presence of irritated or visibly inflamed scalp.
  • Having had hair chemically treated (including colored hair, permed hair, etc.) within the month prior to study.

Key Trial Info

Start Date :

August 1 1997

Trial Type :

INTERVENTIONAL

End Date :

June 1 2000

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT00176969

Start Date

August 1 1997

End Date

June 1 2000

Last Update

June 2 2014

Active Locations (1)

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1

University of Minnesota

Minneapolis, Minnesota, United States, 55455