Status:
COMPLETED
Effects of Ligands on Human Hair Follicles Grafted Onto SCID Mice
Lead Sponsor:
Hordinsky, Maria K., MD
Conditions:
Alopecia
Eligibility:
MALE
18-65 years
Phase:
PHASE1
Brief Summary
The purpose of this study is to determine if immunophilin ligands may have the potential to reverse hair loss.
Detailed Description
Preliminary experiments in C57BL/6J mice showed that immunophilin ligand FK506 and its non-immunosuppressive analogs, GP11046 and GP11511 were capable of promoting telogen to anagen transition. Since ...
Eligibility Criteria
Inclusion
- Healthy men ages 18-65 with Hamilton type IV or V alopecia
Exclusion
- Individuals who do not meet the inclusion criteria.
Key Trial Info
Start Date :
July 1 2003
Trial Type :
INTERVENTIONAL
End Date :
September 1 2004
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT00177099
Start Date
July 1 2003
End Date
September 1 2004
Last Update
November 13 2006
Active Locations (1)
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1
University of Minnesota
Minneapolis, Minnesota, United States, 55455