Status:

COMPLETED

Coordinating Center for Enhancing ADRD Caregiving

Lead Sponsor:

University of Pittsburgh

Collaborating Sponsors:

National Institute on Aging (NIA)

National Institute of Nursing Research (NINR)

Conditions:

Dementia

Alzheimer Disease

Eligibility:

All Genders

21+ years

Phase:

NA

Brief Summary

Established in 1995, Resources for Enhancing Alzheimer's Caregiver Health (REACH) is a unique, multi-site research program sponsored by the National Institute on Aging (NIA) and the National Institute...

Detailed Description

Six sites (Boston, Birmingham, Memphis, Miami, Palo Alto, and Philadelphia) developed and evaluated a variety of multi-component interventions for family caregivers of persons with Alzheimer's Disease...

Eligibility Criteria

Inclusion

  • CORE CARE RECIPIENT INCLUSION/EXCLUSION CRITERIA
  • Inclusion criteria:
  • NINCDS -ADRDA Criteria for Alzheimer's Disease and/or DSM IV Criteria for Alzheimer's Disease or other dementia or MMSE score \< 23.
  • Functional impairment: presence of two IADL or one ADL impairments.
  • Exclusion criteria:
  • Any terminal illness with life expectancy \< 6 months
  • Active treatment (chemotherapy, radiation therapy) for cancer
  • More than three acute medical hospitalizations in past year (not for psychiatric or Alzheimer's Disease related admission)
  • Schizophrenia (onset of delusions before age 45)
  • Dementia secondary to head trauma (probable)
  • Blindness or deafness if either disability prohibits them from completion of data collection or participation in the interventions
  • MMSE = 0 and bedbound (confined to a bed or chair for \> 22 hours per day, for at least 4 of the past 7 days)
  • Planned nursing home admission in 6 months
  • CORE CAREGIVER INCLUSION/EXCLUSION CRITERIA
  • Inclusion criteria:
  • Age: 21 years and older
  • Language: site specific, must be competent either orally or written
  • Lives with care recipient
  • Family member
  • Gender: Palo Alto/Los Angeles will only enroll women. All other sites will enroll men and women
  • Must have a telephone
  • At enrollment, plan to remain in area for the duration of the intervention and follow-up
  • Caregiver role of at least 6 months
  • Provides \> 4 hours of supervision or direct assistance per day for the care recipient
  • Exclusion criteria:
  • Any terminal illness with life expectancy \< 6 months
  • Active treatment (chemotherapy, radiation therapy) for cancer
  • More than three acute medical hospitalizations in past year
  • Involved in another clinical trial of interventions for caregivers (non drug study)
  • Second Level Review If the caregiver has been inconsistent with answers or repeated answers, then the interviewer will administer the SPMSQ. The interviewer will then discuss with the PI and coordinate another phone call with the caregiver.
  • If in the course of the telephone screen the research assistant believes that there may be difficulties for the caregiver regarding travel arrangements, hesitancy to answer questions, or other specific items (site-specific indications), the research assistant will refer to the PI for review.
  • All potential caregivers will receive a follow-up phone call for second level exclusion from the trial when appropriate.

Exclusion

    Key Trial Info

    Start Date :

    September 1 1996

    Trial Type :

    INTERVENTIONAL

    End Date :

    November 1 2001

    Estimated Enrollment :

    1200 Patients enrolled

    Trial Details

    Trial ID

    NCT00178165

    Start Date

    September 1 1996

    End Date

    November 1 2001

    Last Update

    September 15 2005

    Active Locations (5)

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    Page 1 of 2 (5 locations)

    1

    University of Alabama at Birmingham

    Birmingham, Alabama, United States, 35294-2041

    2

    Stanford University and Veterans Affairs

    Menlo Park, California, United States, 94025

    3

    University of Miami at Miami, Center on Adult Development and Aging

    Miami, Florida, United States, 33136

    4

    Thomas Jefferson University at Philadelphia, Center for Applied Research on Aging and Health

    Philadelphia, Pennsylvania, United States, 19107