Status:
COMPLETED
Nitric Oxide and the Autonomic Nervous System
Lead Sponsor:
Vanderbilt University
Conditions:
Hypertension
Pure Autonomic Failure
Eligibility:
All Genders
18-85 years
Phase:
NA
Brief Summary
The amount of blood flowing to the different parts of the body is regulated by the autonomic (automatic) nerves and by local factors produced by the blood vessels. Nitric oxide (NO) is one of the most...
Eligibility Criteria
Inclusion
- Adult subjects.
- 18 to 85 years.
- Non-smokers or long term smokers for specific aim 6.
- Drug-free.
- Long term hypertension in specific substudy 3, patients with autonomic failure in specific aims 4 and 5, diabetes mellitus in specific aim 5.
Exclusion
- Being on any medication other than antihypertensives (for hypertensives), autonomic medications (for autonomic failure \[AF\] patients), insulin or other treatment for diabetes (for diabetic patients).
- Having pulmonary, renal, hematopoietic, hepatic and/or cardiac disease.
Key Trial Info
Start Date :
August 1 2002
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2008
Estimated Enrollment :
112 Patients enrolled
Trial Details
Trial ID
NCT00178919
Start Date
August 1 2002
End Date
August 1 2008
Last Update
June 4 2013
Active Locations (1)
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1
Autonomic Dysfunction Center
Nashville, Tennessee, United States, 37232