Status:
COMPLETED
Relationship Between the Biological and Psychological Correlates of PTSD
Lead Sponsor:
University of Pennsylvania
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Post-Traumatic Stress Disorder
Eligibility:
FEMALE
18+ years
Phase:
PHASE2
Brief Summary
This study will determine the effectiveness of immediate treatment with prolonged exposure therapy (PE) versus delaying treatment with PE in altering neuroendocrine-related symptoms of post-traumatic ...
Detailed Description
Post-Traumatic Stress Disorder (PTSD) is a psychiatric disorder that can occur following exposure to a traumatic incident in which grave physical harm occurred or was threatened. PTSD is marked by cle...
Eligibility Criteria
Inclusion
- Chronic post-traumatic stress disorder
- Minimum of 3 months passed since traumatic event happened
- Agree to use an effective form of contraception throughout the study
Exclusion
- History of schizophrenia, bipolar disorder, or cognitive dysfunction due to a general medical condition
- History of alcohol or other drug abuse or dependence within 3 months of study enrollment
- Mental retardation or other pervasive developmental disorder
- Unwillingness or inability to discontinue current psychotherapy treatment (stable psychiatric medication therapy taken during the study is not criteria for exclusion)
- Significant risk of violence or history of serious violent behavior within one year of study enrollment
- Medically unstable condition
- Continuing intimate relationship with the perpetrator when the trauma involves assault
- At risk for suicide risk
- Currently pregnant
Key Trial Info
Start Date :
September 1 2001
Trial Type :
INTERVENTIONAL
End Date :
July 1 2007
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00183300
Start Date
September 1 2001
End Date
July 1 2007
Last Update
October 6 2015
Active Locations (1)
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1
Center for the Treatment and Study of Anxiety, University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104