Status:

TERMINATED

Classification and Characterization of Patients Treated With Efalizumab for Plaque Psoriasis

Lead Sponsor:

Norwegian University of Science and Technology

Conditions:

Plaque Psoriasis

Eligibility:

All Genders

18+ years

Brief Summary

The main objectives of the project are: * To classify patients suffering from plaque psoriasis responding on a given treatment (efalizumab) based upon reduction in Psoriasis Area and severity Index (...

Detailed Description

This is an investigator initiated,prospective, longitudinal, observation study. Before starting treatment with efalizumab we will record factors such as demographic data, type of psoriasis, previous t...

Eligibility Criteria

Inclusion

  • moderate to severe plaque psoriasis for more than six months
  • eligible for efalizumab treatment according to current Norwegian guidelines

Exclusion

  • Pregnant or breast-feeding patients
  • Patients with a history of uncontrolled bacterial, viral, fungal or atypical mycobacterial infection.
  • Patients suffering from HIV, Hepatitis B or C, active tuberculosis, hepatic cirrhosis and hospital admission for cardiac disease, stroke or pulmonary disease within last year.
  • Patients with history of cancer in the preceding 5 years, including lymphoproliferative disorders. patients with history of fully resolved basal cell or squamous cell skin cancer may be enrolled.
  • Patients with impaired renal or hepatic function.

Key Trial Info

Start Date :

May 1 2005

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 1 2008

Estimated Enrollment :

96 Patients enrolled

Trial Details

Trial ID

NCT00184366

Start Date

May 1 2005

End Date

July 1 2008

Last Update

January 19 2012

Active Locations (1)

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1

Dep of dermatology, St Olavs Hospital

Trondheim, Norway, 7006