Status:
COMPLETED
Switching From Morphine to Methadone. A Clinical, Pharmacological and Pharmacogenetic Study
Lead Sponsor:
Norwegian University of Science and Technology
Conditions:
Cancer
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
Cancer patients on morphine for chronic pain, with side effects or unsatisfactory pain relief, will be rotated to Methadone. We will try to find out what is the best methode to rotate, and the equival...
Detailed Description
This study is based on the clinical observation that patients who are not well controlled on morphine or oxycodone may benefit from switching to another opioid, in this case methadone. Although the me...
Eligibility Criteria
Inclusion
- • Malignant disease.
- On morphine and in need of opioid rotation. (A patient in need of opioid rotation is defined as having insufficient pain control with or without unacceptable side effects from opioids).
- Able to complete the planned assessment schedules.
- Above 18 years of age.
- If out-patient, the patient lives with someone who can observe him/her.
- Given informed consent according to the ethical guidelines.
Exclusion
- Not able to read or write in Norwegian
- The patient has participated in a clinical study 4 weeks prior to inclusion
Key Trial Info
Start Date :
August 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2009
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT00184496
Start Date
August 1 2004
End Date
September 1 2009
Last Update
February 28 2014
Active Locations (1)
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1
St Olavs Hospital
Trondheim, Trondheim, Norway, 7006