Status:
COMPLETED
Obesity, Weight Loss, and Cardiovascular Disease Risk
Lead Sponsor:
Stanford University
Conditions:
Obesity
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The goal of the study is to define the roles played by resistance to insulin-mediated glucose disposal (insulin resistance) and circulating plasma insulin concentrations in: 1) ability to lose weight;...
Detailed Description
While obesity, insulin resistance, and diabetes are highly associated, it is not clear whether insulin resistance and compensatory hyperinsulinemia play important roles in the tendency to gain weight ...
Eligibility Criteria
Inclusion
- BMI 30-35
- age 35-65
- nondiabetic by fasting plasma glucose concentration
- no active major organ diseases
- insulin resistant or insulin sensitive
Exclusion
- anemia
- pregnant
- major organ disease
- active malignancy
- eating disorder
- active psychiatric illness
- chronic inflammatory conditions
Key Trial Info
Start Date :
October 1 2000
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 31 2017
Estimated Enrollment :
58 Patients enrolled
Trial Details
Trial ID
NCT00186459
Start Date
October 1 2000
End Date
August 31 2017
Last Update
December 4 2024
Active Locations (1)
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1
Stanford University School of Medicine
Stanford, California, United States, 94305