Status:
UNKNOWN
Magnetic Stimulation as a Treatment for Auditory Hallucinations in Schizophrenia
Lead Sponsor:
St. Joseph's Healthcare Hamilton
Conditions:
Schizophrenia
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
Schizophrenia is a chronic, severe, and disabling brain disease. Auditory hallucinations are the most frequent symptoms with an incident of 50% to 70% in patients. Transcranial Magnetic Stimulation (...
Detailed Description
We hypothesize that: True treatment with rTMS will have significant decrease in auditory hallucinations versus sham treatment over the temporoparietal cortex. FMRI will highlight areas of activation ...
Eligibility Criteria
Inclusion
- Schizophrenia
- Auditory hallucinations occuring more than 5 times per day
- Adequate (6 weeks) trial of antipsychotic medication
- Including at least 1 atypical antipsychotic medication
- Medication stable for 4 weeks prior to commencement of the study
- Competent to consent
Exclusion
- history of seizure disorder in patient or first degree relative
- recent head injury
- Acute suicidality
- Alcohol or substance abuse
- Implanted pacemaker or metal in head or neck
- Pregnancy
Key Trial Info
Start Date :
November 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2015
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00186771
Start Date
November 1 2004
End Date
January 1 2015
Last Update
July 28 2011
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
St. Joseph's Healthcare, rTMS Laboratory, 100 West Fifth Street
Hamilton, Ontario, Canada, L8N 3K7
2
St. Joseph's Healthcare, rTMS Laboratory, 100 West Fifth Street
Hamilton, Ontario, Canada, L8N 3K7