Status:
COMPLETED
Therapy for Children With Advanced Stage High Risk Neuroblastoma
Lead Sponsor:
St. Jude Children's Research Hospital
Collaborating Sponsors:
National Institutes of Health (NIH)
Conditions:
Neuroblastoma
Eligibility:
All Genders
Up to 18 years
Phase:
PHASE2
Brief Summary
This is a Phase II pilot study of chemotherapy and surgery for children with advanced stage high-risk neuroblastoma utilizing topotecan during an upfront window and other active agents during inductio...
Detailed Description
In this prospective phase II trial, topotecan is administered intravenously daily for 5 days for each of 2 consecutive weeks for two cycles in an upfront treatment window. Patients subsequently will r...
Eligibility Criteria
Inclusion
- Advanced stage,high-risk neuroblastoma
- Histologic proof of neuroblastoma
- Adequate renal function
- ECOG performance status 0-2
Exclusion
- Previous therapy
Key Trial Info
Start Date :
October 1 1997
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2001
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00186849
Start Date
October 1 1997
End Date
April 1 2001
Last Update
May 20 2009
Active Locations (1)
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1
St. Jude Children's Research Hospital
Memphis, Tennessee, United States, 38105