Status:
COMPLETED
A Severity-Adapted Clinical Trial of Diminished Bone Mineral Density in Acute Lymphoblastic Leukemia Survivors
Lead Sponsor:
St. Jude Children's Research Hospital
Conditions:
Leukemia, Lymphoblastic, Acute
Osteoporosis
Eligibility:
All Genders
Phase:
PHASE3
Brief Summary
Research studies have shown that children who are long-term survivors of childhood leukemia may be at greater risk for early bone loss called osteoporosis. This bone loss may lead to a greater risk of...
Detailed Description
The main objectives of the study are: * To estimate, using quantitative computed tomography (QCT), the prevalence of diminished bone mineral density (BMD) in patients treated with contemporary, proto...
Eligibility Criteria
Inclusion
- Patient is a survivor of acute lymphoblastic leukemia.
- Patient was treated on St. Jude Children's Research Hospital's Total XI, XII, or XIII treatment protocol.
- Patient is at least five years out from completion of therapy and is in first remission
Exclusion
- Active disease
- Pregnant or lactating females
- Inability to chew and swallow pills
- Currently taking more than 800 mg supplemental calcium or 800 IU vitamin D
- Anemia
Key Trial Info
Start Date :
July 1 2000
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2011
Estimated Enrollment :
429 Patients enrolled
Trial Details
Trial ID
NCT00186901
Start Date
July 1 2000
End Date
September 1 2011
Last Update
May 10 2017
Active Locations (3)
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1
St. Jude Children's Research Hospital
Memphis, Tennessee, United States, 38105
2
Metabolic Bone Center at the University of Tennessee
Memphis, Tennessee, United States, 38163
3
Preventive Medicine, University of Tennessee
Memphis, Tennessee, United States, 38163