Status:
COMPLETED
CHIPS (Control of Hypertension in Pregnancy Study): A Pilot Trial
Lead Sponsor:
Sunnybrook Health Sciences Centre
Collaborating Sponsors:
Canadian Institutes of Health Research (CIHR)
Conditions:
Transient Hypertension, Pregnancy
Eligibility:
FEMALE
18-48 years
Phase:
NA
Brief Summary
Prior to undertaking CHIPS which will be a large and difficult trial, we believe we need to first determine whether clinicians will comply with the interventions of 'less tight' and 'tight' control of...
Detailed Description
To determine whether 'less tight' control of mild-moderate non-proteinuric maternal hypertension, aiming for a diastolic blood pressure (dBP) of 100mmHg, can decrease the risks of adverse perinatal ou...
Eligibility Criteria
Inclusion
- dBP 90-109mmHg due to pre-existing or gestational hypertension; live fetus(es); and 20-33+6 weeks.
Exclusion
- dBP consistently \< 85mmHg by home BP monitoring; severe systolic hypertension; proteinuria; contraindication to either arm of the trial or to prolongation of pregnancy; or known lethal/major fetal anomaly.
Key Trial Info
Start Date :
April 1 2003
Trial Type :
INTERVENTIONAL
End Date :
December 1 2005
Estimated Enrollment :
132 Patients enrolled
Trial Details
Trial ID
NCT00187395
Start Date
April 1 2003
End Date
December 1 2005
Last Update
March 12 2009
Active Locations (1)
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1
Maternal Infant and Reproducting Health Research Unit - CHIPS Data Coordinating Centre
Toronto, Ontario, Canada, M5G 1N8