Status:
COMPLETED
Phosphate Intake's Effect on the Skeletal System - Pilot
Lead Sponsor:
University of California, San Francisco
Conditions:
Healthy
Kidney Failure, Chronic
Eligibility:
MALE
21-65 years
Phase:
NA
Brief Summary
The purpose of this study is to determine the effects of different amounts of phosphorus in the diet on hormones that control phosphorus and bone health both in men who are healthy and in ones who hav...
Detailed Description
Chronic kidney disease affects 11% of the US population; over half of those affected have skeletal manifestations of their renal disease. Renal osteodystrophy is a complex disease, in which multiple m...
Eligibility Criteria
Inclusion
- Healthy Men 21-65 years old with Creatinine clearance \> 70 ml/min/1.73 m2 as calculated using the equation derived from the Modification of Diet in Renal Disease (MDRD) study
- Men 21-65 years old with Creatinine clearance between 30 and 59 ml/min/1.73 m2 as calculated using the equation derived from the MDRD study31
Exclusion
- Medications affecting bone metabolism
- Abnormal liver or GI function
- Extreme electrolyte abnormalities
- BMI \>30 kg/m2
Key Trial Info
Start Date :
March 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2008
Estimated Enrollment :
27 Patients enrolled
Trial Details
Trial ID
NCT00187629
Start Date
March 1 2004
End Date
July 1 2008
Last Update
October 9 2013
Active Locations (1)
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1
University of California
San Francisco, California, United States, 94143