Status:
UNKNOWN
Psychoeducation Versus Cognitive-Behavioral Therapy in Bipolar Disorder
Lead Sponsor:
University Health Network, Toronto
Collaborating Sponsors:
Stanley Medical Research Institute
Conditions:
Bipolar Disorder
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
To examine the impact of cognitive-behavioural therapy on both the episodic and functional outcome of bipolar disorder, in combination with pharmacotherapy. Primary Hypothesis is twofold: 1. Cogniti...
Detailed Description
Objective: To compare the impact of cognitive -behavioral therapy to that of properly structured psycho education on the 'illness burden' and functional outcome of bipolar disorder, in combination wi...
Eligibility Criteria
Inclusion
- Bipolar I or II
- Currently either in remission or subsyndromally ill (Hamilton Depression Scale-17\<14; Clinician Administered Rating Scale for Mania\<12).
- Age eighteen to sixty.
- Significant symptoms and/or episodes on at least two occasions in the past three years.
- Grade six education, able to understand English, and Folstein Minimental Score Exam \> 26 to ensure cognitive ability to participate.
- On mood-stabilizing medication.
Exclusion
- Substance dependence meeting Diagnostic and Statistical Manual of Mental Disorders-IV criteria within the last three months.
- Acutely highly suicidal or homicidal.
- Serious other medical condition that would render pharmacotherapy or psychotherapy very difficult such as cancer, severe diabetes, etc.
- Severe antisocial or borderline personality disorder (personality disorder per se is not exclusionary). Subjects may have other axis I disorders, but bipolar disorder must be the principal disorder requiring treatment.
Key Trial Info
Start Date :
July 1 2002
Trial Type :
INTERVENTIONAL
End Date :
August 1 2006
Estimated Enrollment :
210 Patients enrolled
Trial Details
Trial ID
NCT00188838
Start Date
July 1 2002
End Date
August 1 2006
Last Update
September 16 2005
Active Locations (6)
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1
University of British Columbia, Department of Psychiatry
Vancouver, British Columbia, Canada, V6T-2A1
2
St. Joseph's Healthcare, CMHS
Hamilton, Ontario, Canada, L8N-3K7
3
Centre for Addiction and Mental Health
Toronto, Ontario, Canada, M5T-1R8
4
University Health Network
Toronto, Ontario, Canada, M5T-2S8