Status:
COMPLETED
Randomized Trial of Nasal Continuous Positive Airway Pressure or Synchronized Nasal Ventilation in Premature Infants.
Lead Sponsor:
University of Manitoba
Collaborating Sponsors:
Health Sciences Centre Foundation, Manitoba
Conditions:
Apnea
Infant, Premature
Eligibility:
All Genders
Phase:
PHASE3
Brief Summary
Very premature infants uniformly do not have mature functioning lungs to breathe well nor mature regulation mechanisms to breathe regularly. Assistance with a mechanical respirator is common. However,...
Detailed Description
Early extubation of premature infants may limit the deleterious effects of positive pressure ventilation. The primary cause of failure of extubation (and the need for reintubation) is apnea of prematu...
Eligibility Criteria
Inclusion
- Premature infants with birth weight 500-1250 grams
- first attempt at extubation
Exclusion
- (clinical suspicion or documented diagnosis of:
- neuromuscular disease
- chromosomal abnormality
- or any congenital anomalies that would affect ability to be extubated from mechanical ventilation via endotracheal tube (i.e. congenital cardiac anomalies, choanal atresia).
Key Trial Info
Start Date :
November 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2007
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT00188968
Start Date
November 1 2004
End Date
February 1 2007
Last Update
May 2 2007
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Health Sciences Centre
Winnipeg, Manitoba, Canada, R3A 1R9
2
St. Boniface General Hospital
Winnipeg, Manitoba, Canada