Status:

COMPLETED

Effect of Two Versus Three Pneumococcal Conjugate Vaccinations

Lead Sponsor:

UMC Utrecht

Collaborating Sponsors:

Netherlands: Ministry of Health, Welfare and Sports

Netherlands Vaccine Institute

Conditions:

Streptococcus Pneumoniae Infection

Eligibility:

All Genders

2-3 years

Phase:

PHASE3

Brief Summary

Two( 2) or three (3) instead of four vaccinations before the age of 6 months with pneumococcal conjugate vaccine are presumed to protect children against invasive pneumococcal disease like meningitis,...

Detailed Description

Two(2 and 4 months) and three vaccinations (2,4 and 11 months) with 7-valent pneumococcal conjugate vaccine Prevnar in infants are presumed to provide about 90% protection against invasive pneumococca...

Eligibility Criteria

Inclusion

  • Newborn infants eligible for participation in the national infant vaccination program in the Netherlands

Exclusion

  • exclusion from the national vaccination program because of the presence of
  • a medical condition requiring treatment that can interfere with the effect of vaccinations
  • known or suspected allergy to components of the pneumococcal conjugate vaccine
  • known or suspected immunodeficiency disease
  • previous treatment with plasma or immunoglobulins
  • previous vaccinations other than hepatitis B vaccinations
  • coagulation disorders

Key Trial Info

Start Date :

June 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

1005 Patients enrolled

Trial Details

Trial ID

NCT00189020

Start Date

June 1 2005

Last Update

August 22 2011

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