Status:

TERMINATED

Effects of Gabapentin in the Treatment of Neuropathic Pain on Driving Performance and Cognition

Lead Sponsor:

UMC Utrecht

Collaborating Sponsors:

Utrecht University

Conditions:

Chronic Neuropathic Pain

Eligibility:

All Genders

30-60 years

Phase:

PHASE4

Brief Summary

The aim of this study was to explore the effects of pain on the one hand and the effects of treatment of pain with gabapentin (900, 1200, 1800 or 2400 mg) on the other hand on actual driving performan...

Detailed Description

Numerous studies demonstrate neuropsychological impairment in patients with chronic pain, particularely on measures assessing attentional capacity, processing speed and psychomotor speed. About 50% of...

Eligibility Criteria

Inclusion

  • age, responder to gabapentin,succesfully treated with gabapentin at least 4 weeks before start of study, minimal VAS pain intensity scores of 4 cm on a 10 cm scale, driving licence, driving experience, fluently speaking Dutch, normal vision, right-handed

Exclusion

  • alcohol- or drug dependence, use of other psychotropic medication, use of illicit drugs, psychological or physical disorder other than pain or pain-related, excessive smoking and drinking

Key Trial Info

Start Date :

April 1 2003

Trial Type :

INTERVENTIONAL

End Date :

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT00189072

Start Date

April 1 2003

Last Update

September 16 2005

Active Locations (1)

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1

University of Utrecht

Utrecht, Utrecht, Netherlands, 3508 TB